⚕️ Information: This page is for healthcare professionals only. The content is a reference for clinical decision support; It does not replace the clinician's patient-specific assessment.

🧭 Clinical Decision Algorithms

Interactive algorithms that provide step-by-step approach, treatment and drug dose recommendations by selecting disease and clinical criteria.

🔬 Scientific Clinical Guidelines

In-depth cited clinical reviews from ACOG, RCOG, NICE, SMFM, Cochrane and UpToDate.

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ATA 2026 · ACOG PB 223

Thyroid Diseases During Pregnancy

Hypothyroidism and hyperthyroidism on one page: TSH thresholds, levothyroxine dose escalation, PTU–methimazole selection, TRAb-based fetal monitoring, thyroid storm and postpartum thyroiditis.

Clinical Review22 min
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ACOG, SMFM, ISUOG

Cervical Insufficiency and Cerclage

Diagnostic methods based on history, ultrasound and physical examination; thresholds and pitfalls of cervical length measurement; The evidence base for the choice between vaginal progesterone and cerclage.

Clinical Review22 min reading
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ACOG PB 183 RCOG GTG 52

Postpartum Hemorrhage (PPH)

PPH management from cumulative blood loss threshold to uterotonic doses, from the first three hour rule of tranexamic acid to massive transfusion targets.

Clinical Review22 min reading
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ACOG, WHO, US MEC

Postpartum Care (Fourth Trimester) and Contraception

Differentiation of normal course and warning signs in puerperium, timing of follow-up, mental health and cardiometabolic screening, choice of contraceptive method in breastfeeding women.

Clinical Review23 min reading
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ACOG PB 217 RCOG GTG 73

Membrane Rupture: Term PROM and PPROM

PROM management, from the false positive problem of biomarker tests to latency antibiotic regimens and the 34–37 week birth timing debate.

Clinical Review15 min reading
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ACOG, RCOG, SOGC, CNGOF

Breech Presentation and External Cephalic Version (ECV)

Timing and success determinants of ECV in term breech presentation, evidence base for the decision on mode of delivery, and criteria and technique of vaginal breech delivery in selected cases.

Clinical Review20 min reading
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FDA PLLR 2015

Drug Use During Pregnancy and Teratogenicity

Summary of background risk, critical developmental windows, removal of FDA letter categories, pharmacokinetics in pregnancy, and commonly used drug groups.

Clinical Review18 min
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CDC 2021 ECCI 2024

Infections and Screening During Pregnancy

Guideline-based summary of vertical transmission rates, where screening decisions differ by institution, prenatal diagnosis timing, and treatment thresholds.

Clinical Review25 min reading
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ASRM 2026 · ESHRE 2023

Early Pregnancy Loss and Recurrent Pregnancy Loss

CRL 7 mm and sac 25 mm thresholds, waiting–medication–surgery comparison, institution differentiation in anti-D decision, and recurrent pregnancy loss workup panel.

Clinical Review13 min
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ACOG PB 193 (2018, 2025 approval)

Ectopic Pregnancy

From diagnostic criteria and hCG elevation rate to methotrexate protocols, from the choice of salpingostomy–salpingectomy to interstitial and cesarean scar pregnancy.

Clinical Review14 min
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ACOG PB 107 · Cochrane 2020

Labor Induction and Postterm Pregnancy

Guideline-based management of induction, from cervical ripening doses to oxytocin regimens, from the ARRIVE discussion to the decision to induce at 41 weeks.

Clinical Review17 min reading
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ACOG 831 SMFM #46

Amniotic Fluid Abnormalities

Summary of AFI and SDP thresholds, impact of measurement method on induction rate, etiology, amnioreduction, and birth timing decisions.

Clinical Review17 min
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ACOG PB 226 · SMFM #74 · ISPD 2023

Prenatal Screening Tests (CFTS, Quad, NIPT/cfDNA)

First-trimester combined (double), quadruple, and NIPT methods and performance; side-by-side guideline comparison (ACOG/NICE/SMFM/ISPD/ACMG); positive NIPT → invasive confirmation; Salomon 2019 updated procedure-related loss risk; GRADE certainty summary.

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ACOG PB 222

Preeclampsia and Hypertensive Disorders of Pregnancy

Diagnostic criteria, sFlt-1/PlGF pathophysiology, low-dose aspirin prophylaxis, MgSO4 seizure prophylaxis, acute antihypertensives and timing of birth.

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ACOG PB 190 · ADA 2026

Gestational Diabetes Mellitus (GDM)

One-step 75g and two-step 50g/100g screening, diagnostic thresholds, glycemic targets, insulin/oral agents, fetal monitoring and postpartum screening.

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ACOG CO 797

Group B Streptococcus (GBS) and Intrapartum Prophylaxis

36 0/7–37 6/7 weeks screening, intrapartum antibiotic indications, penicillin regimens and penicillin allergy algorithm.

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ACOG PB 233

Anemia and Iron Deficiency in Pregnancy

Trimester-based hemoglobin thresholds, differential diagnosis, oral and intravenous iron therapy, ferritin threshold and transfusion indications.

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RCOG GTG 37a · ACOG PB 196

Venous Thromboembolism: Risk and Prophylaxis

Hypercoagulability in pregnancy, RCOG risk scoring, LMWH doses, mechanical prophylaxis and timing of neuraxial anesthesia.

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ACOG PB 227 · ISUOG

Fetal Growth Restriction (FGR)

Delphi consensus definition, etiology, Doppler assessment (umbilical/MCA/CPR/ductus venosus), and timing of birth according to Doppler finding.

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ACOG PB 234 CO 713

Preterm Labor and Birth: Prevention and Management

Cervical length/fFN, vaginal progesterone and cerclage, antenatal corticosteroids, MgSO4 neuroprotection and tocolytic selection.

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ACOG PB 181

Rh(D) Isoimmunization and Anti-D Prophylaxis

Screening, event-based anti-D Ig doses and timing, MCA-PSV monitoring in sensitized pregnancy, and fetal RHD genotyping.

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ACOG PB 205

Caesarean Section and VBAC (TOLAC)

Safely reducing primary cesarean section, TOLAC candidate selection, prediction of success, risk of uterine rupture, and placenta accreta spectrum.

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ACOG Clinical Consensus 8

Prenatal Care and Antenatal Screening

Initial visit panel, visit schedule (traditional/telehealth), aneuploidy screening (cfDNA/NIPT), anomaly screening, and routine testing schedule.

🧮 Clinical Calculators

Guideline-based, evidence-based obstetrics calculation tools. Methods, sources, and limitations are documented in each.

📚 Guideline and Literature Sources

Official sources of the international obstetric and maternal-fetal medicine authorities (external links).

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